Recently, the research paper entitled "Non-ribosomal peptide biosynthetic potential of the nematode symbiont Photorhabdus" by Ao-Qi Du and Ti-Ti Ying was accepted by Environmental Microbiology Reports. This paper systematically analyzed the non-ribosomal peptide synthetic potential of 81 Photorhabdus strains and found that these genomes contained a large number of NRPS BGCs, which encoded more than 350 novel peptides containing more than four amino acids. In addition, the basic structure of the core polypeptides that Photorhabdus strains can synthesize is determined by a molecular network. This paper lays the foundation for target discovery and in-depth mining of NRPS natural products in Photorhabdus strains. This work was completed under the guidance of Prof. Hong Wang, and Dr. Bin Wei.
